Corneal Degeneration, also known as degenerative corneal opacity, is related to keratopathy and granular corneal dystrophy. An important gene associated with Corneal Degeneration is SLC4A4 (Solute Carrier Family 4 Member 4), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Plasma lipoprotein assembly, remodeling, and clearance. The drugs Riboflavin and Folic acid have been mentioned in the context of this disorder. Affiliated tissues include eye and endothelial, and related phenotypes are Increased free cholesterol and homeostasis/metabolism