Cornelia De Lange Syndrome (BDLS)

Cornelia De Lange Syndrome, also known as brachmann-de lange syndrome, is related to cornelia de lange syndrome 1 and cornelia de lange syndrome 3 with or without midline brain defects. An important gene associated with Cornelia De Lange Syndrome is NIPBL (NIPBL Cohesin Loading Factor), and among its related pathways/superpathways are Cell Cycle, Mitotic and EML4 and NUDC in mitotic spindle formation. The drugs Acetylcysteine and Cysteine have been mentioned in the context of this disorder. Affiliated tissues include eye and bone, and related phenotypes are intellectual disability and high palate