Cardiac Valvular Dysplasia 1, also known as cardiac valvular defect, developmental, is related to cardiac valvular dysplasia 2, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Cardiac Valvular Dysplasia 1 is PLD1 (Phospholipase D1). The drugs Amiodarone and Vecuronium have been mentioned in the context of this disorder. Affiliated tissues include heart and kidney, and related phenotypes are mitral regurgitation and ventricular septal defect