Cardiovascular System Disease, also known as abnormality of the cardiovascular system, is related to vascular disease and coronary heart disease 1. An important gene associated with Cardiovascular System Disease is KCNQ1 (Potassium Voltage-Gated Channel Subfamily Q Member 1), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Mesenchymal Stem Cells and Lineage-specific Markers. The drugs Dimethyl fumarate and Desflurane have been mentioned in the context of this disorder. Affiliated tissues include heart and endothelial, and related phenotypes are homeostasis/metabolism and muscle