Cardiomyopathy, Familial Restrictive, 2, also known as restrictive cardiomyopathy 2, is related to familial isolated restrictive cardiomyopathy and mitochondrial dna depletion syndrome 12b. An important gene associated with Cardiomyopathy, Familial Restrictive, 2 is RCM2 (Cardiomyopathy, Familial Restrictive, 2).