Cerebellar Disease

Cerebellar Disease, also known as cerebellar dysfunction, is related to spinocerebellar ataxia 1 and spinocerebellar ataxia 8, and has symptoms including ataxia, dysarthria and cerebellar cognitive affective syndrome. An important gene associated with Cerebellar Disease is AFG3L2 (AFG3 Like Matrix AAA Peptidase Subunit 2), and among its related pathways/superpathways are Neuroscience and Maturation of protein E. The drugs Interferon beta-1a and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include cerebellum and spinal cord, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased ionizing radiation sensitivity