Capillary Leak Syndrome (SCLS)

Alias:
Systemic Capillary Leak Syndrome
Clarkson Disease
Capillary Hyperpermeability Syndrome
Idiopathic Capillary Leak Syndrome
Scls
Capillary Leak Syndrome with Monoclonal Gammopathy
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Capillary Leak Syndrome, also known as systemic capillary leak syndrome, is related to compartment syndrome and pulmonary edema. An important gene associated with Capillary Leak Syndrome is TLN1 (Talin 1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Tazobactam and Piperacillin have been mentioned in the context of this disorder. Affiliated tissues include kidney and bone, and related phenotypes are pedal edema and leukocytosis
Related ID:
MESH:D019559

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Adult
<1/1000000
22
265
--

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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