Central Precocious Puberty, also known as gonadotropin-dependant precocious puberty, is related to precocious puberty, central, 2 and precocious puberty, central, 1. An important gene associated with Central Precocious Puberty is KISS1R (KISS1 Receptor), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Megestrol acetate and Leuprolide have been mentioned in the context of this disorder. Affiliated tissues include pituitary and hypothalamus, and related phenotypes are hypothyroidism and short stature