Central Sleep Apnea, also known as sleep apnea, central, is related to sleep apnea and atrial fibrillation, and has symptoms including apnea An important gene associated with Central Sleep Apnea is PHOX2B (Paired Like Homeobox 2B), and among its related pathways/superpathways are Peptide hormone metabolism and Hepatic ABC Transporters. The drugs Opium and Naltrexone have been mentioned in the context of this disorder. Affiliated tissues include heart and spinal cord, and related phenotypes are nervous system and homeostasis/metabolism