Cannabis Dependence, also known as marijuana abuse, is related to alcohol use disorder and conduct disorder. An important gene associated with Cannabis Dependence is CNR1 (Cannabinoid Receptor 1), and among its related pathways/superpathways are Methylphenidate Pathway, Pharmacodynamics and Anandamide biosynthesis and metabolism. The drugs Acetylcysteine and Ethanol have been mentioned in the context of this disorder. Affiliated tissues include brain and prefrontal cortex.