Congenital Nad Deficiency Disorder (VCRL)

Congenital Nad Deficiency Disorder, also known as vertebral, cardiac, renal, and limb defects syndrome, is related to vertebral, cardiac, renal, and limb defects syndrome 1 and congenital vertebral-cardiac-renal anomalies syndrome. An important gene associated with Congenital Nad Deficiency Disorder is KYNU (Kynureninase), and among its related pathways/superpathways are superpathway of tryptophan utilization and NAD metabolism. Related phenotype is Increased shRNA abundance (Z-score > 2).