Congenital Heart Defects, Multiple Types, 6, also known as transposition of the great arteries, dextro-looped 3, is related to epilepsy, progressive myoclonic, 8 and heart, malformation of. An important gene associated with Congenital Heart Defects, Multiple Types, 6 is GDF1 (Growth Differentiation Factor 1). Affiliated tissues include heart and lung, and related phenotypes are coarctation of aorta and tetralogy of fallot