Congenital Factor Xii Deficiency

Congenital Factor Xii Deficiency, also known as congenital hageman factor deficiency, is related to factor xii deficiency and thrombophilia due to thrombin defect. An important gene associated with Congenital Factor Xii Deficiency is F12 (Coagulation Factor XII), and among its related pathways/superpathways is 5q35 copy number variation. Affiliated tissues include heart, and related phenotypes are prolonged partial thromboplastin time and reduced factor xii activity