Congenital Heart Defects, Hamartomas of Tongue, and Polysyndactyly (CHDTHP)

Congenital Heart Defects, Hamartomas of Tongue, and Polysyndactyly, also known as ostravik-lindemann-solberg syndrome, is related to isolated focal cortical dysplasia type ii and multilocular clear cell renal cell carcinoma. An important gene associated with Congenital Heart Defects, Hamartomas of Tongue, and Polysyndactyly is WDPCP (WD Repeat Containing Planar Cell Polarity Effector), and among its related pathways/superpathways are Akt Signaling and Regulation of TP53 Activity. The drugs Everolimus and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include tongue and heart, and related phenotypes are patent ductus arteriosus and subvalvular aortic stenosis