Congenital Hydrocephalus, also known as hydrocephalus, nonsyndromic, autosomal recessive 1, is related to congenital communicating hydrocephalus and dandy-walker syndrome, and has symptoms including back pain, headache and pain. An important gene associated with Congenital Hydrocephalus is CCDC88C (Coiled-Coil Domain Containing 88C), and among its related pathways/superpathways are Wnt / Hedgehog / Notch and Hedgehog signaling events mediated by Gli proteins. The drugs Glycopyrronium and Nitrous oxide have been mentioned in the context of this disorder. Affiliated tissues include brain and spinal cord, and related phenotypes are hydrocephalus and macrocephaly