Congenital Contractures

Congenital Contractures, also known as congenital contracture, is related to congenital contractures of the limbs and face, hypotonia, and developmental delay and polyhydramnios. An important gene associated with Congenital Contractures is DST (Dystonin), and among its related pathways/superpathways is Smooth Muscle Contraction. Affiliated tissues include skin and skeletal muscle, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased hepcidin::fluc mRNA expression