Complement Component 8 Deficiency, also known as c8 deficiency, is related to complement component 8 deficiency, type ii and complement component 8 deficiency, type i. An important gene associated with Complement Component 8 Deficiency is C8A (Complement C8 Alpha Chain), and among its related pathways/superpathways are Complement cascade and Initial triggering of complement. Affiliated tissues include spinal cord and brain.