Complement Factor I Deficiency, also known as complement component 3 inactivator deficiency, is related to afibrinogenemia, congenital and meningitis. An important gene associated with Complement Factor I Deficiency is CFI (Complement Factor I), and among its related pathways/superpathways are Innate Immune System and Diseases of hemostasis. The drugs Androgens and Insulin have been mentioned in the context of this disorder. Affiliated tissues include kidney and skin, and related phenotypes are decreased circulating complement factor i concentration and decreased circulating complement c3 concentration