Clivus Chordoma, also known as chordoma of clivus, is related to chordoma and tuberous sclerosis 1, and has symptoms including headache An important gene associated with Clivus Chordoma is COTL1 (Coactosin Like F-Actin Binding Protein 1), and among its related pathways/superpathways is Non-integrin membrane-ECM interactions. The drugs Afatinib and Protein Kinase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include bone and lymph node.