Cleft Palate, Cardiac Defects, and Impaired Intellectual Development (CPCMR)

Cleft Palate, Cardiac Defects, and Impaired Intellectual Development, also known as cardiac malformation, cleft lip/palate, microcephaly, and digital anomalies, is related to cleft palate, cardiac defects, and intellectual disabillity and chromosome 2q35 duplication syndrome. An important gene associated with Cleft Palate, Cardiac Defects, and Impaired Intellectual Development is MEIS2 (Meis Homeobox 2). Affiliated tissues include heart and eye, and related phenotypes are intellectual disability and gastroesophageal reflux