Cleft Palate with or Without Ankyloglossia, X-Linked, also known as cleft palate with ankyloglossia, is related to cleft palate, isolated and cleft lip. An important gene associated with Cleft Palate with or Without Ankyloglossia, X-Linked is TBX22 (T-Box Transcription Factor 22). Affiliated tissues include tongue and bone, and related phenotype is craniofacial.