Cleft Lip/palate (FLP)

Cleft Lip/palate(来自ICD-11)
别称:
Cleft Lip and Palate
Cleft Lip-Alveolus-Palate Syndrome
Alveolar Cleft Lip and Palate
Flp
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Cleft Lip/palate, also known as cleft lip and palate, is related to ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1 and cleft lip/palate-ectodermal dysplasia syndrome. An important gene associated with Cleft Lip/palate is DLX4 (Distal-Less Homeobox 4), and among its related pathways/superpathways are Signal Transduction and PAK Pathway. The drugs Fentanyl and Rocuronium have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are abnormality of dental eruption and delayed speech and language development
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相关ID:
ICD11:1481115868

基础信息

遗传方式
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患病率/发病率
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参考文献
MALACARDS
--
Newborn
1-5/10000
22
276
3

疾病表征

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靶点药物

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临床阶段
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疾病模型

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MGI
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