Cleft Lip/palate (FLP)

Alias:
Cleft Lip and Palate
Cleft Lip-Alveolus-Palate Syndrome
Alveolar Cleft Lip and Palate
Flp
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Cleft Lip/palate, also known as cleft lip and palate, is related to ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1 and cleft lip/palate-ectodermal dysplasia syndrome. An important gene associated with Cleft Lip/palate is DLX4 (Distal-Less Homeobox 4), and among its related pathways/superpathways are Signal Transduction and PAK Pathway. The drugs Fentanyl and Rocuronium have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are abnormality of dental eruption and delayed speech and language development
Related ID:
ICD11:1481115868

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Newborn
1-5/10000
22
281
3

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
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IF
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