Cleft Lip

Cleft Lip(来自ICD-11)
别称:
Labium Leporinum
Cheiloschisis
Cleft Lip Without Cleft Palate, Unilateral
Cleft Lip Without Cleft Palate, Bilateral
Cleft Lip, Unilateral, Complete
Cleft Lip Without Cleft Palate
Isolated Cleft Lip, Unilateral
Complete Unilateral Cleft Lip
Isolated Cleft Lip, Bilateral
Congenital Fissure of Lip
Isolated Cleft Lip
Hare Lip
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Cleft Lip, also known as labium leporinum, is related to ankyloblepharon-ectodermal defects-cleft lip/palate and cleft lip/palate-ectodermal dysplasia syndrome. An important gene associated with Cleft Lip is SETD5 (SET Domain Containing 5), and among its related pathways/superpathways are Overview of interferons-mediated signaling pathway and Mesodermal commitment pathway. The drugs Fentanyl and Sevoflurane have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are Increased shRNA abundance (Z-score > 2) and growth/size/body region
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相关ID:
MESH:D002971
ICD11:1520576126

基础信息

遗传方式
发病时间
患病率/发病率
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参考文献
MALACARDS
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Unknown
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43
447
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靶点药物

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临床阶段
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MGI
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