Cleidocranial Dysplasia 1 (CLCD1)

Cleidocranial Dysplasia 1, also known as cleidocranial dysplasia, is related to parietal foramina with cleidocranial dysplasia and trichodentoosseous syndrome. An important gene associated with Cleidocranial Dysplasia 1 is RUNX2 (RUNX Family Transcription Factor 2), and among its related pathways/superpathways are Gene expression (Transcription) and TGF-beta receptor signaling in skeletal dysplasias. Affiliated tissues include bone and bone marrow, and related phenotypes are frontal bossing and skeletal dysplasia