Celiac Disease 1, also known as celiac disease, is related to autoimmune disease and type 1 diabetes mellitus, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Celiac Disease 1 is HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ Beta 1), and among its related pathways/superpathways are Allograft rejection and CD28 co-stimulation. The drugs Prucalopride and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include small intestine and bone, and related phenotypes are vitamin b12 deficiency and cerebral calcification