Calcification of Joints and Arteries (CALJA)

Alias:
Hereditary Arterial and Articular Multiple Calcification Syndrome
Calja
Arterial Calcification Due to Deficiency of Cd73
Arterial Calcification Due to Cd73 Deficiency
Arterial Calcification and Distal Joint Calcification
Acdc
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Calcification of Joints and Arteries, also known as hereditary arterial and articular multiple calcification syndrome, is related to arteries, anomalies of and peripheral artery disease. An important gene associated with Calcification of Joints and Arteries is NT5E (5'-Nucleotidase Ecto), and among its related pathways/superpathways are Endochondral ossification with skeletal dysplasias and Glucose / Energy Metabolism. The drugs Moxifloxacin and Enzyme Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include prostate and brain, and related phenotypes are abnormal vascular morphology and arterial occlusion
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
Adult
<1/1000000
10
96
3

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
Year
IF
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