Colchicine Resistance, also known as colchicine sensitivity, is related to familial mediterranean fever and brucellosis. An important gene associated with Colchicine Resistance is ABCB1 (ATP Binding Cassette Subfamily B Member 1), and among its related pathways/superpathways are Synthesis of bile acids and bile salts and Blood-Brain Barrier and Immune Cell Transmigration: Overview. The drugs Colchicine and Tubulin Modulators have been mentioned in the context of this disorder. Affiliated tissues include heart and bone marrow.