Charcot-Marie-Tooth Disease, Demyelinating, Type 1i, also known as charcot-marie-tooth neuropathy, type 1i, is related to polr3-related leukodystrophy and charcot-marie-tooth disease. An important gene associated with Charcot-Marie-Tooth Disease, Demyelinating, Type 1i is POLR3B (RNA Polymerase III Subunit B). Affiliated tissues include brain, and related phenotypes are intellectual disability and dysarthria