Charcot-Marie-Tooth Disease X-Linked Recessive 4 (CMTX4)

Charcot-Marie-Tooth Disease X-Linked Recessive 4, also known as x-linked charcot-marie-tooth disease type 4, is related to charcot-marie-tooth disease, x-linked recessive, 4, with or without cerebellar ataxia and mitochondrial encephalomyopathy. An important gene associated with Charcot-Marie-Tooth Disease X-Linked Recessive 4 is AIFM1 (Apoptosis Inducing Factor Mitochondria Associated 1), and among its related pathways/superpathways is Peroxisomal lipid metabolism. Affiliated tissues include skeletal muscle and brain, and related phenotypes are skeletal muscle atrophy and decreased nerve conduction velocity