Chronic Graft Versus Host Disease

Chronic Graft Versus Host Disease, also known as chronic graft-versus-host disease, is related to leukemia, chronic myeloid and skin disease. An important gene associated with Chronic Graft Versus Host Disease is CCR7 (C-C Motif Chemokine Receptor 7), and among its related pathways/superpathways are ERK Signaling and MIF Mediated Glucocorticoid Regulation. The drugs Fludarabine and Busulfan have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and bone, and related phenotypes are thickened skin and poor wound healing