Chiari Malformation

Chiari Malformation, also known as chiari malformations, is related to arachnoiditis and hydrocephalus. An important gene associated with Chiari Malformation is COL5A2 (Collagen Type V Alpha 2 Chain), and among its related pathways/superpathways are Signal Transduction and Phospholipase-C Pathway. The drugs Polyestradiol phosphate and Estradiol have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and cerebellum, and related phenotypes are Decreased viability in pancreas lineage and growth/size/body region