Chronic Recurrent Multifocal Osteomyelitis, also known as chronic multifocal osteomyelitis, is related to inflammatory bowel disease 1 and bone disease. An important gene associated with Chronic Recurrent Multifocal Osteomyelitis is IL1R1 (Interleukin 1 Receptor Type 1), and among its related pathways/superpathways are Infectious disease and Innate Immune System. The drugs Zoledronic acid and Leflunomide have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are osteomyelitis and bone pain