Churg-Strauss Syndrome (EGPA)

Churg-Strauss Syndrome, also known as eosinophilic granulomatosis with polyangiitis, is related to vasculitis and polyarteritis nodosa, and has symptoms including asthma An important gene associated with Churg-Strauss Syndrome is PRTN3 (Proteinase 3), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and Akt Signaling. The drugs Cyclophosphamide and Azathioprine have been mentioned in the context of this disorder. Affiliated tissues include lung and heart, and related phenotypes are sinusitis and congestive heart failure