Chondrocalcinosis

Chondrocalcinosis, also known as pseudogout, is related to chondrocalcinosis 2 and familial calcium pyrophosphate deposition, and has symptoms including joint stiffness An important gene associated with Chondrocalcinosis is CCAL1 (Chondrocalcinosis 1 (Calcium Pyrophosphate-Deposition Disease, Early Onset Osteoarthritis)), and among its related pathways/superpathways are Interleukin-4 and Interleukin-13 signaling and Inflammasomes. The drugs Prednisone and Povidone K30 have been mentioned in the context of this disorder. Affiliated tissues include bone and b cells, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and homeostasis/metabolism