Cholestasis, Progressive Familial Intrahepatic, 11, is also known as pfic11. An important gene associated with Cholestasis, Progressive Familial Intrahepatic, 11 is SEMA7A (Semaphorin 7A (John Milton Hagen Blood Group)). Affiliated tissues include liver, and related phenotypes are increased serum bile acid concentration and elevated circulating alanine aminotransferase concentration