Childhood Acute Megakaryoblastic Leukemia, also known as pediatric non-down syndrome acute megakaryoblastic leukemia, is related to leukemia, acute monocytic and acute megakaryoblastic leukemia without down syndrome. An important gene associated with Childhood Acute Megakaryoblastic Leukemia is CBFA2T3 (CBFA2/RUNX1 Partner Transcriptional Co-Repressor 3).