Childhood T-Cell Acute Lymphoblastic Leukemia

Alias:
T-Cell Childhood Acute Lymphoblastic Leukemia
Childhood Precursor T-Lymphoblastic Lymphoma/leukemia
T-Cell Childhood Acute Lymphocytic Leukemia
Childhood T Lymphoblastic Leukemia/lymphoma
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Childhood T-Cell Acute Lymphoblastic Leukemia, also known as t-cell childhood acute lymphoblastic leukemia, is related to lymphoblastic lymphoma and severe combined immunodeficiency. An important gene associated with Childhood T-Cell Acute Lymphoblastic Leukemia is TAL1 (TAL BHLH Transcription Factor 1, Erythroid Differentiation Factor), and among its related pathways/superpathways are T-cell activation SARS-CoV-2 and IL12-mediated signaling events. The drugs Cyclophosphamide and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include t cells and bone marrow, and related phenotypes are immune system and hematopoietic system
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Basic Information

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Reference
MALACARDS
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Unknown
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15
129
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Gene & Mutation

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References Literature

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