Cholangitis, Primary Sclerosing, also known as primary sclerosing cholangitis, is related to autoimmune pancreatitis and choledocholithiasis, and has symptoms including icterus An important gene associated with Cholangitis, Primary Sclerosing is SEMA4D (Semaphorin 4D), and among its related pathways/superpathways are Defensins and Response of Mtb to phagocytosis. The drugs Bezafibrate and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include liver and small intestine, and related phenotypes are autoimmunity and cholestasis