Cholestasis, Intrahepatic, of Pregnancy, 1 (ICP1)

Alias:
Icp1
Intrahepatic Cholestasis of Pregnancy 1
Recurrent Intrahepatic Cholestasis of Pregnancy
Cholestasis, Intrahepatic, of Pregnancy, Type 1
Cholestasis of Pregnancy, Intrahepatic 1
Cholestasis, Pregnancy-Related, 1
Pregnancy Related Cholestasis 1
Pregnancy-Related Cholestasis
Cholestasis of Pregnancy
Obstetric Cholestasis
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Cholestasis, Intrahepatic, of Pregnancy, 1, also known as icp1, is related to progressive familial intrahepatic cholestasis and intrahepatic cholestasis of pregnancy, and has symptoms including pruritus of pregnancy An important gene associated with Cholestasis, Intrahepatic, of Pregnancy, 1 is ATP8B1 (ATPase Phospholipid Transporting 8B1), and among its related pathways/superpathways is tRNA Aminoacylation. The drugs Metronidazole and Metformin have been mentioned in the context of this disorder. Affiliated tissues include liver and small intestine, and related phenotypes are elevated hepatic transaminase and jaundice
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Unknown
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9
32
17

Medical Symptom

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Gene & Mutation

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Disease Model

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MGI
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References Literature

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