Cholesteatoma of External Ear, also known as external canal cholesteatoma, is related to cholesteatoma of middle ear and sapho syndrome. An important gene associated with Cholesteatoma of External Ear is IL1A (Interleukin 1 Alpha), and among its related pathways/superpathways are Cellular Senescence and IL-1 Family Signaling Pathways. Affiliated tissues include skin.