Chagas Disease

Chagas Disease, also known as american trypanosomiasis, is related to trypanosomiasis and leishmaniasis, and has symptoms including fever and pruritus. An important gene associated with Chagas Disease is CYP51A1 (Cytochrome P450 Family 51 Subfamily A Member 1), and among its related pathways/superpathways are ERK Signaling and TGF-Beta Pathway. The drugs Warfarin and Acetylsalicylic acid have been mentioned in the context of this disorder. Affiliated tissues include heart and colon, and related phenotypes are splenomegaly and hepatomegaly