Cogan Syndrome

Cogan Syndrome, also known as oculovestibuloauditory syndrome, is related to interstitial keratitis and vasculitis, and has symptoms including fever, fatigue and eye manifestations. An important gene associated with Cogan Syndrome is NPHP4 (Nephrocystin 4), and among its related pathways/superpathways are Loss of Nlp from mitotic centrosomes and Organelle biogenesis and maintenance. The drugs Ethanol and Lecithin have been mentioned in the context of this disorder. Affiliated tissues include eye and bone, and related phenotypes are photophobia and vertigo