Cocaine Dependence

Cocaine Dependence is related to polysubstance abuse and personality disorder. An important gene associated with Cocaine Dependence is SLC6A3 (Solute Carrier Family 6 Member 3), and among its related pathways/superpathways are Transmission across Chemical Synapses and Acetylcholine binding and downstream events. The drugs Biperiden and Lamotrigine have been mentioned in the context of this disorder. Affiliated tissues include brain and prefrontal cortex, and related phenotypes are nervous system and homeostasis/metabolism