C1 Inhibitor Deficiency

C1 Inhibitor Deficiency, also known as angioedemas, hereditary, is related to acquired angioedema and chronic spontaneous urticaria, and has symptoms including edema and peau d'orange. An important gene associated with C1 Inhibitor Deficiency is SERPING1 (Serpin Family G Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Omalizumab and Lactitol have been mentioned in the context of this disorder. Affiliated tissues include brain and small intestine.