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ENBrittle Bone Disorder (OI)
Alias:
Osteogenesis Imperfecta
Brittle Bone Disease
Fragilitas Ossium
Lobstein Disease
Oi
Glass Bone Disease
Lobstein's Disease
Osteopsathyrosis
Osteogenesis Imperfecta, Recessive Perinatal Lethal
Osteogenesis Imperfecta, Dominant Perinatal Lethal
White Blue Sclera - Fragility of Bone - Deafness
Blue Sclera with Fragility of Bone and Deafness
Oi - [osteogenesis Imperfecta]
Brittle Bone Syndrome
Osteitis Fragilitans
Lobstein's Syndrome
Vrolik's Disease
Ossium Fragility
Vrolik Disease
Bony Fragility
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Brittle Bone Disorder, also known as osteogenesis imperfecta, is related to osteogenesis imperfecta, type i and osteogenesis imperfecta, type ii, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Brittle Bone Disorder is COL1A2 (Collagen Type I Alpha 2 Chain), and among its related pathways/superpathways are Pleural mesothelioma and Collagen chain trimerization. The drugs Pamidronic acid and Alendronic acid have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are macrocephaly and gait disturbance
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