Bartter Syndrome, Type 3 (BARTS3)

Bartter Syndrome, Type 3, also known as bartter disease type 3, is related to bartter syndrome, type 4b, neonatal, with sensorineural deafness and bartter syndrome, type 4a, neonatal, with sensorineural deafness, and has symptoms including polyuria and generalized muscle weakness. An important gene associated with Bartter Syndrome, Type 3 is CLCNKB (Chloride Voltage-Gated Channel Kb), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Ion channel transport. Affiliated tissues include kidney and retina, and related phenotypes are hypokalemia and hypocalciuria