Brain Small Vessel Disease is related to brain small vessel disease 3 and brain small vessel disease 2. An important gene associated with Brain Small Vessel Disease is COL4A1 (Collagen Type IV Alpha 1 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. Affiliated tissues include brain and fetal brain, and related phenotypes are nervous system and respiratory system