Bone Giant Cell Sarcoma, also known as giant cell tumor of bone, malignant, is related to benign giant cell tumor and malignant giant cell tumor. An important gene associated with Bone Giant Cell Sarcoma is H3-3A (H3.3 Histone A), and among its related pathways/superpathways are Pre-NOTCH Expression and Processing and Cellular Senescence. Affiliated tissues include bone, and related phenotype is normal.