Bone Disease

Bone Disease, also known as disorder of skeletal system, is related to brittle bone disorder and osteopetrosis, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Bone Disease is DANCR (Differentiation Antagonizing Non-Protein Coding RNA), and among its related pathways/superpathways are Vitamin D receptor pathway and Endochondral ossification with skeletal dysplasias. The drugs Calcium carbonate and Elvitegravir have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are Increased NF-kappaB reporter expression and homeostasis/metabolism