B-Lymphoblastic Leukemia/lymphoma (B-ALL)

Alias:
B Lymphoblastic Leukemia/lymphoma
B-All
Precursor B Lymphoblastic Lymphoma/leukemia
Lbl - [lymphoblastic Lymphoma]
Lymphoblastic B-Cell Lymphoma
Lymphoblastic Lymphoma, Nos
Common Precursor B All
B-Precursor Lymphoma
Pro-B All
C-All
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
B-Lymphoblastic Leukemia/lymphoma, also known as b lymphoblastic leukemia/lymphoma, is related to b-lymphoblastic leukemia/lymphoma with hypodiploidy and b-lymphoblastic leukemia/lymphoma with hyperdiploidy. An important gene associated with B-Lymphoblastic Leukemia/lymphoma is KMT2A (Lysine Methyltransferase 2A), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Vindesine and Rituximab have been mentioned in the context of this disorder. Affiliated tissues include b lymphoblasts and bone marrow, and related phenotypes are Decreased viability and Increased shRNA abundance (Z-score > 2)
Related ID:
ICD11:381281608

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Unknown
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42
719
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Medical Symptom

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Description
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Gene & Mutation

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Disease Model

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MGI
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Publications
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References Literature

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